While doing so the cursor stays in place. So : You choose between one of the six independent profiles with the top buttons, set whatever parameters you like, assign a hotkey to the big button at the bottom, then while sculpting you hold that hotkey down and adjust a chosen parameter with X axis and another one with Y. The adjust plugin shipped with zBrush did not do it for me, so I started to write my own one, and there it is. I wanted to have a tool which would do it more naturally, without having to relate to precise numbers, just like like in Photoshop with Alt or Maya/Mudbox holding B key. ZBrush has got a wonderful seamless smooth workflow, and to me adjusting draw size or focal shift with a slider is quite annoying.
